PeproTech重组人GDF-3 (Animal Free) 500ug-细胞/细菌培养-试剂-生物在线
美国PeproTech(派普泰克)公司中国代表处
PeproTech重组人GDF-3 (Animal Free) 500ug

PeproTech重组人GDF-3 (Animal Free) 500ug

商家询价

产品名称： PeproTech重组人GDF-3 (Animal Free) 500ug

英文名称： Recombinant Human GDF-3

产品编号： AF-120-22

产品价格： 0

产品产地： 美国

品牌商标： PeproTech

更新时间： null

使用范围： null

美国PeproTech(派普泰克)公司中国代表处
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  • 邮编 : 215123
  • 所在区域 : 江苏
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  • 邮箱 : peprotech.infochina@thermofisher.com
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Recombinant Human GDF-3
 
Catalog Number:
AF-120-22
Synonyms:
Growth/Differentiation, Factor-3, Vgr-2
Description:
GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9.  Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers.  GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue.  The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes.  Recombinant human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains. Manufactured using all non-animal reagents.
AA Sequence:
AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.  The ED50 for this effect is 100-150 ng/ml.
 
 
 
 
Research Interests:
 
 
Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.