Cd40lg monoclonal antibody, clone MR1
产品名称： Cd40lg monoclonal antibody, clone MR1
英文名称： Cd40lg monoclonal antibody, clone MR1
产品编号： MAB3231
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Hamster monoclonal antibody raised against Cd40lg.
- Immunogen:
- Native Cd40lg from mouse Th1 clone D1.6.
- Host:
- Hamster
- Reactivity:
- Mouse
- Specificity:
- CD154 (Mouse CD40 ligand/gp39), Mr 39-KDa.
- Form:
- Liquid
- Isotype:
- IgG
- Storage Buffer:
- In 100 mM BBS, pH 8.2
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- An essential role for gp39, the ligand for CD40, in thymic selection.
Foy TM, Page DM, Waldschmidt TJ, Schoneveld A, Laman JD, Masters SR, Tygrett L, Ledbetter JA, Aruffo A, Claassen E, Xu JC, Flavell RA, Oehen S, Hedrick SM, Noelle RJ.J Exp Med. 1995 Nov 1;182(5):1377-88.
- 2.
- In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.
Foy TM, Shepherd DM, Durie FH, Aruffo A, Ledbetter JA, Noelle RJ.J Exp Med. 1993 Nov 1;178(5):1567-75.
- 3.
- The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome.
Aruffo A, Farrington M, Hollenbaugh D, Li X, Milatovich A, Nonoyama S, Bajorath J, Grosmaire LS, Stenkamp R, Neubauer M, et al..Cell. 1993 Jan 29;72(2):291-300.
- Applications
- Flow Cytometry
- Partially purified spleen T cells from BALB/c mice were incubated with either hamster IgG or plate-bound Cd3e monoclonal antibody, clone 145-2C11 for 7 hours at 37°C. The cells were then harvested, double-stained with Cd40lg monoclonal antibody, clone MR1 (Cat # MAB3231)-FITC and anti-CD4+8-R-PE, and analyzed by flow cytometry.