Human Growth Factors & Cytokines
Recombinant Human GDF-3





 





		Synonyms :
Growth/Differentiation Factor-3



		Description :
GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9.  Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers.  GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue.  The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes.  Recombinant human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.



		Catalog #:
120-22



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.  The ED50 for this effect is 100-150 ng/ml.



                AA Sequence :
AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG 



		PubMed Link :
GDF-3+OR+GDF3


Country of Origin :
USA
















        Size A
5μg
$80 
 


 



        Size B
20μg
$195 
 


 



        Size C
1mg
$3900 
 


 















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.