CARD8 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： CARD8 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： CARD8 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00022900-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human CARD8 protein.
- Immunogen:
- CARD8 (AAH56891.1, 1 a.a. ~ 392 a.a) full-length human protein.
- Sequence:
- MEKKECPEKSSSSEEELPRRDSGSSRNIDASKLIRLQGSRKLLVDNSIRELQYTKTGIFFQAEACVTNDTVYRELPCVSETLCDISHFFQEDDETEAEPLLFRAVPECQLSGGDIPSVSEEQESSEGQDSGDICSEENQIVSSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLVRDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHSISLQAGEVDVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLIYYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSANLKVMPKWISSL
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of CARD8 expression in transfected 293T cell line (H00022900-T02) by CARD8 MaxPab polyclonal antibody.
Lane 1: CARD8 transfected lysate(44.00 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 22900
- GeneBank Accession#:
- BC056891
- Protein Accession#:
- AAH56891.1
- Gene Name:
- CARD8
- Gene Alias:
- CARDINAL,DACAR,DKFZp779L0366,Dakar,FLJ18119,FLJ18121,KIAA0955,MGC57162,NDPP,NDPP1,TUCAN
- Gene Description:
- caspase recruitment domain family, member 8
- Omim ID:
- 609051
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- CARD inhibitor of NF-kappaB-activating ligands,CARD8 isoform T47,CARD8 isoform T51,CARD8 isoform T60,apoptotic protein NDPP1,tumor up-regulated CARD-containing antagonist of caspase nine
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Arthritis
- Arthritis, Rheumatoid
- Bacterial Infections
- Colitis, Ulcerative
- Colorectal Neoplasms
- Crohn Disease
- Crohn's disease
- Disease Progression
- Encephalitis
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Inflammatory Bowel Diseases
- Tobacco Use Disorder