QKI polyclonal antibody
产品名称: QKI polyclonal antibody
英文名称: QKI polyclonal antibody
产品编号: PAB7106
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of QKI.
- Immunogen:
- A synthetic peptide corresponding to human QKI.
- Sequence:
- ETKEKPKPTPDY-C
- Host:
- Goat
- Theoretical MW (kDa):
- 37.7, 35.1, 36, 35.2
- Reactivity:
- Mouse
- Specificity:
- This antibody is expected to recognize all reported isoforms (NP_006766.1, NP_996735.1, NP_996736.1, NP_996737.1).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:64000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Function of quaking in myelination: regulation of alternative splicing.
Wu JI, Reed RB, Grabowski PJ, Artzt K.Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4233-8. Epub 2002 Mar 26.
- Entrez GeneID:
- 9444
- Protein Accession#:
- NP_006766.1;NP_996735.1;NP_996736.1;NP_996737.1
- Gene Name:
- QKI
- Gene Alias:
- DKFZp586I0923,Hqk,QK,QK1,QK3
- Gene Description:
- quaking homolog, KH domain RNA binding (mouse)
- Omim ID:
- 609590
- Gene Ontology:
- Hyperlink
- Gene Summary:
- QKI belongs to a family of RNA-binding proteins that have an HNRNPK (MIM 600712) homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1; MIM 602489) and SF1 (MIM 601516) (Chen and Richard, 1998 [PubMed 9671495]). QKI proteins regulate RNA splicing, export of target RNAs from the nucleus, translation of proteins, and RNA stability (Lauriat et al., 2008 [PubMed 17918747]).[supplied by OMIM
- Other Designations:
- OTTHUMP00000017581,OTTHUMP00000017582,OTTHUMP00000017583,RNA binding protein HQK,homolog of mouse quaking QKI (KH domain RNA binding protein),quaking homolog, KH domain RNA binding
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