重组大鼠IL-4-RNAi技术-试剂-生物在线
上海沪震实业有限公司
重组大鼠IL-4

重组大鼠IL-4

商家询价

产品名称： 重组大鼠IL-4

英文名称： Recombinant Rat Interleukin-4

产品编号： HZ4705

产品价格： 0

产品产地： 中国/上海

品牌商标： 沪震生物

更新时间： 2023-08-17T10:24:20

使用范围： null

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 重组大鼠IL-4

中文名称：重组大鼠IL-4
英文名称：Recombinant Rat Interleukin-4
产品规格：5μg
分子量：Approximately 14.0kDa,a single non-glycosylated polypeptide chain containing 125 amino acids.
储存条件：冷冻（-20℃）

概述

Interleukin-4(IL-4)is a pleiotropic cytokine that induces differentiation of naive helper T cells(Th0 cells)to Th2 cells and produced by mast cells,activated T cells and bone marrow stromal cells.It has many biological roles,including the stimulation of activated B-cell and T-cell proliferation,and the differentiation of CD4+ T-cells into Th2 cells.IL-4 can enhance both secretion and cell surface expression of IgE and IgG1 and also regulates the expression of the low affinity Fc receptor for IgE(CD23)on both lymphocytes and monocytes.The rat IL-4 shares about 40%~45%a.a.sequence identity with human,mouse,rhesus macaque IL-4 and they are species-specific in their activities.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观 Sterile Filtered White lyophilized(freeze-dried)powder.
纯度 ＞95%by SDS-PAGE and HPLC analyses.
来源 Escherichia coli.
生物活性 Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using rat splenocytes is less than 1.0ng/ml,corresponding to a specific activity of>1.0×106 IU/mg.
成分 Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4,5%trehalose.
内毒素 Less than 1 EU/μg of rRtIL-4 as determined by LAL method.
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列 HGCNDSPLRE IINTLNQVTE KGTPCTEMFV PDVLTATRNT TENELICRAS RVLRKFYFPR DVPPCLKNKS GVLGELRKLC RGVSGLNSLR SCTVNESTLT TLKDFLESLK SILRGKYLQS CTSMS

 

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