BMPR2 monoclonal antibody (M02), clone 2C10
产品名称: BMPR2 monoclonal antibody (M02), clone 2C10
英文名称: BMPR2 monoclonal antibody (M02), clone 2C10
产品编号: H00000659-M02
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant BMPR2.
- Immunogen:
- BMPR2 (NP_001195.2, 939 a.a. ~ 1037 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- NSLDLSATNVLDGSSIQIGESTQDGKSGSGEKIKKRVKTPYSLKRWRPSTWVISTESLDCEVNNNGSNRAVHSKSSTAVYLAEGGTATTMVSKDIGMNC
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
- MSDS:
- Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 659
- GeneBank Accession#:
- NM_001204
- Protein Accession#:
- NP_001195.2
- Gene Name:
- BMPR2
- Gene Alias:
- BMPR-II,BMPR3,BMR2,BRK-3,FLJ41585,FLJ76945,PPH1,T-ALK
- Gene Description:
- bone morphogenetic protein receptor, type II (serine/threonine kinase)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq
- Other Designations:
- BMP type II receptor,bone morphogenetic protein receptor type II,bone morphogenetic protein receptor type-2,primary pulmonary hypertension 1,serine/threonine kinase,type II activin receptor-like kinase,type II receptor for bone morphogenetic protein-4
- Related Disease
- Adenomatous Polyposis Coli
- Anemia, Sickle Cell
- Anemia, sickle cell
- Anoxia
- Cardiovascular Diseases
- Cleft Lip
- Cleft Palate
- Colon cancer
- Colonic Neoplasms
- Colorectal Neoplasms
- Genetic Predisposition to Disease
- Heart Defects, Congenital
- Heart Diseases
- Hypertension
- Hypertension, Pulmonary
- Liver Cirrhosis
- Microsatellite Instability
- Obesity
- Ovarian Failure, Premature