FITC标记的DEF8蛋白抗体
产品名称： FITC标记的DEF8蛋白抗体
英文名称： Anti-DEF8/FITC
产品编号： HZ-14241R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DEF8/FITC Conjugated antibody
FITC标记的DEF8蛋白抗体
| 英文名称 | Anti-DEF8/FITC |
| 中文名称 | FITC标记的DEF8蛋白抗体 |
| 别 名 | DEF-8; Def8; Def 8; DEFI8_HUMAN; Differentially expressed in FDCP 8 homolog; FLJ20186; MGC104349. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 59kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DEF8 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: DEF8 is a 512 amino acid protein that is expressed at highest levels in peripheral leukocytes. It is expressed as five isoforms as a result of alternative splicing events. The gene encoding DEF8 maps to chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. Similarity: Belongs to the DEF8 family. Contains 2 phorbol-ester/DAG-type zinc fingers. Database links: Entrez Gene: 54849 Human SwissProt: Q6ZN54 Human Unigene: 62771 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
DEF8是一种在外周血白细胞中最高表达的512氨基酸蛋白。它作为替代剪接事件的结果被表示为五种异构体。编码DEF8的基因定位于染色体16，在大约9000万碱基对中编码900多个基因，占人类细胞DNA的近3%，并且与多种遗传病有关。罕见的Rubinstein-Taybi综合征与16号染色体有关，克罗恩病也是，一种可能涉及NOD2基因的胃肠道炎症状态。系统性红斑狼疮和许多其它与染色体16的着丝粒周区相关的自身免疫性疾病导致SLC5A11被鉴定为潜在的自身免疫调节剂。