APC (Human) Recombinant Protein (Q01)
产品名称： APC (Human) Recombinant Protein (Q01)
英文名称： APC (Human) Recombinant Protein (Q01)
产品编号： H00000324-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human APC partial ORF ( NP_000029, 2744 a.a. - 2843 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- NPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV
- Theoretical MW (kDa):
- 36.85
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 324
- GeneBank Accession#:
- NM_000038
- Protein Accession#:
- NP_000029
- Gene Name:
- APC
- Gene Alias:
- BTPS2,DP2,DP2.5,DP3,GS
- Gene Description:
- adenomatous polyposis coli
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq
- Other Designations:
- adenomatosis polyposis coli tumor suppressor
- Interactome
- Related Disease
- Adenocarcinoma
- Adenoma
- Adenomatous Polyposis Coli
- Adenomatous Polyps
- Autistic Disorder
- Barrett Esophagus
- Bone Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Large Cell
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Cell Transformation, Neoplastic
- Chromosomal Instability
- Chromosome Aberrations
- Chromosome Deletion