BICD2 polyclonal antibody
产品名称： BICD2 polyclonal antibody
英文名称： BICD2 polyclonal antibody
产品编号： PAB13388
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BICD2.
- Immunogen:
- A synthetic peptide corresponding to internal region 14 amino acids of human BICD2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice.
Teuling E, van Dis V, Wulf PS, Haasdijk ED, Akhmanova A, Hoogenraad CC, Jaarsma D.Hum Mol Genet. 2008 Sep 15;17(18):2849-62. Epub 2008 Jun 25.
- 2.
- Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2.
Holland PM, Milne A, Garka K, Johnson RS, Willis C, Sims JE, Rauch CT, Bird TA, Virca GD.J Biol Chem. 2002 May 3;277(18):16229-40. Epub 2002 Feb 25.
- 3.
- Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes.
Hoogenraad CC, Akhmanova A, Howell SA, Dortland BR, De Zeeuw CI, Willemsen R, Visser P, Grosveld F, Galjart N.EMBO J. 2001 Aug 1;20(15):4041-54.
- Entrez GeneID:
- 23299
- Protein Accession#:
- CAI41013
- Gene Name:
- BICD2
- Gene Alias:
- KIAA0699,bA526D8.1
- Gene Description:
- bicaudal D homolog 2 (Drosophila)
- Omim ID:
- 609797
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described. [provided by RefSeq
- Other Designations:
- OTTHUMP00000022790,OTTHUMP00000022791,bicaudal D homolog 2,coiled-coil protein BICD2,cytoskeleton-like bicaudal D protein homolog 2,homolog of Drosophila bicaudal D