JUN (phospho S63) Peptide
产品名称: JUN (phospho S63) Peptide
英文名称: JUN (phospho S63) Peptide
产品编号: P1303
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- 所在区域 : 台湾
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of JUN.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S63 of human JUN.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Dot Blot (1:500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases.
Cheng J, Perkins ND, Yeh ET.J Biol Chem. 2005 Apr 15;280(15):14492-8. Epub 2005 Feb 8.
- 2.
- Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts.
Quan T, He T, Voorhees JJ, Fisher GJ.J Biol Chem. 2005 Mar 4;280(9):8079-85. Epub 2004 Dec 3.
- 3.
- Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-kappaB and activator protein-1 repression.
Bladh LG, Liden J, Dahlman-Wright K, Reimers M, Nilsson S, Okret S.Mol Pharmacol. 2005 Mar;67(3):815-26. Epub 2004 Nov 18.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of JUN (phospho S63) polyclonal antibody (Cat # PAB0444) in mouse brain tissue lysate (35 ug/lane). Mouse Phospho-JUN-pS63 (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with JUN (phospho S63) polyclonal antibody (Cat # PAB0444) which was peroxidase-conjugated to the secondary antibody followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Entrez GeneID:
- 3725
- Protein Accession#:
- NP_002219;P05412
- Gene Name:
- JUN
- Gene Alias:
- AP-1,AP1,c-Jun
- Gene Description:
- jun oncogene
- Omim ID:
- 165160
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq
- Other Designations:
- Jun activation domain binding protein,OTTHUMP00000010036,activator protein 1,enhancer-binding protein AP1,v-jun avian sarcoma virus 17 oncogene homolog,v-jun sarcoma virus 17 oncogene homolog
- Gene Pathway
- B cell receptor signaling pathway
- Colorectal cancer
- Epithelial cell signaling in Helicobacter pylori infection
- ErbB signaling pathway
- Focal adhesion
- GnRH signaling pathway
- MAPK signaling pathway
- Neurotrophin signaling pathway
- Pathways in cancer
- Renal cell carcinoma
- T cell receptor signaling pathway
- Toll-like receptor signaling pathway
- Wnt signaling pathway
- Related Disease
- Arthritis, Reactive
- Asthma
- Asthma
- Breast cancer
- Breast Neoplasms
- Bronchiolitis, Viral
- Campylobacter Infections
- Cardiovascular Diseases
- Chronic Disease
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Edema
- Genetic Predisposition to Disease
- Infant, Premature, Diseases
- Kidney Failure, Chronic
- Ovarian Neoplasms
- Respiratory Syncytial Virus Infections