LMAN1 polyclonal antibody
产品名称： LMAN1 polyclonal antibody
英文名称： LMAN1 polyclonal antibody
产品编号： PAB20116
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against recombinant LMAN1.
- Immunogen:
- Recombinant protein corresponding to amino acids of human LMAN1.
- Sequence:
- IGNNGQIHYDHQNDGASQALASCQRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMIIPAQGHFGISAATGGLADDHDVLSFLTFQLTEPGKEP
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Isotype:
- IgG
- Storage Buffer:
- In PBS, pH 7.5 (40% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (1:500-1:1000)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 3998
- Protein Accession#:
- P49257
- Gene Name:
- LMAN1
- Gene Alias:
- ERGIC-53,ERGIC53,F5F8D,FMFD1,MCFD1,MR60,gp58
- Gene Description:
- lectin, mannose-binding, 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq
- Other Designations:
- coagulation factor V-factor VIII combined deficiency,endoplasmic reticulum-golgi intermediate compartment protein 53,intracellular mannose specific lectin
- Related Disease
- Bacteremia
- Birth Weight
- Cardiovascular Diseases
- Chronic Disease
- Colitis, Ulcerative
- Coronary Artery Disease
- Crohn Disease
- Crohn's disease
- Cystic Fibrosis
- Cystic fibrosis
- Diabetes Mellitus, Type 2
- Edema
- Factor V Deficiency
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- Hemophilia A
- Hemophilia A
- Hemorrhage