MGAT1 (C-term) Peptide
产品名称： MGAT1 (C-term) Peptide
英文名称： MGAT1 (C-term) Peptide
产品编号： P1082
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MGAT1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MGAT1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein.
Tan J, D'Agostaro AF, Bendiak B, Reck F, Sarkar M, Squire JA, Leong P, Schachter H.Eur J Biochem. 1995 Jul 15;231(2):317-28.
- 2.
- Cloning and expression of the murine gene and chromosomal location of the human gene encoding N-acetylglucosaminyltransferase I.
Kumar R, Yang J, Eddy RL, Byers MG, Shows TB, Stanley P.Glycobiology. 1992 Aug;2(4):383-93.
- 3.
- Organization and localization to chromosome 5 of the human UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I gene.
Hull E, Sarkar M, Spruijt MP, Hoppener JW, Dunn R, Schachter H.Biochem Biophys Res Commun. 1991 Apr 30;176(2):608-15.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of MGAT1 polyclonal antibody (Cat # PAB4305) in Y-79 cell line lysate . MGAT1 (arrow) was detected using the purified MGAT1 polyclonal antibody (Cat # PAB4305) .
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with MGAT1 polyclonal antibody (Cat # PAB4305) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma .
- Entrez GeneID:
- 4245
- Protein Accession#:
- GNT1_HUMAN
- Gene Name:
- MGAT1
- Gene Alias:
- GLCNAC-TI,GLCT1,GLYT1,GNT-1,GNT-I,MGAT
- Gene Description:
- mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
- Omim ID:
- 160995
- Gene Ontology:
- Hyperlink
- Gene Summary:
- There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase,OTTHUMP00000161546
- Gene Pathway