Human Growth Factors & Cytokines
Recombinant Human soluble TRAIL Receptor-1





 





		Synonyms :
soluble TRAIL Receptor-1, DR4, TNFRSF10A, Apo2



		Description :
TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain, " which can activate the cell's apoptotic machinery.  These receptors are activated by binding to either membrane anchored or soluble TRAIL/Apo2L.  Recombinant human soluble TRAIL Receptor-1/DR4 is a 22.7 kDa protein (215 amino acid residues) consisting of the TNFR homologous, cysteine rich portion of the extracellular domain.



		Catalog #:
310-18



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by its inhibitory effect of IL-8 production in human PBMC by human sTRAIL/Apo2L. 95% inhibition (100 ng/ml of s TRAIL/Apo2L) was reached using a concentration of 100 ng/ml of sTRAIL Receptor-1.



                AA Sequence :
MSGTGAAAAT PSKVWGSSAG RIEPRGGGRG ALPTSMGQHG PSARARAGRA PGPRPAREAS PRLRVHKTFK FVVVGVLLQV VPSSAATIKL HDQSIGTQQW EHSPLGELCP PGSHRSERPG ACNRCTEGVG YTNASQQLFA CLPCTACKSD EEERSPCTTT RNTACQCKPG TFRNDNSAEM CRKCSTGCPR GMVKVKDCTP WSDIECVHKE SGNGHN 



		PubMed Link :
TRAIL+AND+Receptor+AND+DR4


Country of Origin :
USA
















        Size A
10μg
$80 
 


 



        Size B
50μg
$195 
 


 



        Size C
1mg
$1500 
 


 















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.