IL13RA1 polyclonal antibody
产品名称： IL13RA1 polyclonal antibody
英文名称： IL13RA1 polyclonal antibody
产品编号： PAB18396
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of IL13RA1.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding Y405 of human IL13RA1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody is specific to IL13RA1.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration.
Holmqvist K, Cross MJ, Rolny C, Hagerkvist R, Rahimi N, Matsumoto T, Claesson-Welsh L, Welsh M.J Biol Chem. 2004 May 21;279(21):22267-75. Epub 2004 Mar 16.
- 2.
- Identification of specific molecular structures of human immunodeficiency virus type 1 Tat relevant for its biological effects on vascular endothelial cells.
Mitola S, Soldi R, Zanon I, Barra L, Gutierrez MI, Berkhout B, Giacca M, Bussolino F.J Virol. 2000 Jan;74(1):344-53.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of extracts from COLO cells (Lane 1 and 5), HT-29 cells (Lane 2), A-549 cells (Lane 3) and 293 cells (Lane 4), using IL13RA1 polyclonal antibody (Cat # PAB18396).
Peptide "+" means "peptide blocking".
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IL13RA1 polyclonal antibody (Cat # PAB18396).
Peptide "+" means "peptide blocking".
- Entrez GeneID:
- 3597
- Protein Accession#:
- P78552
- Gene Name:
- IL13RA1
- Gene Alias:
- CD213A1,IL-13Ra,NR4
- Gene Description:
- interleukin 13 receptor, alpha 1
- Omim ID:
- 300119
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq
- Other Designations:
- CD213a1 antigen,IL13 receptor alpha-1 chain,OTTHUMP00000023890,bB128O4.2.1 (interleukin 13 receptor, alpha 1)
- Related Disease