TRAF1 monoclonal antibody (M01), clone 2G9-G10
产品名称： TRAF1 monoclonal antibody (M01), clone 2G9-G10
英文名称： TRAF1 monoclonal antibody (M01), clone 2G9-G10
产品编号： H00007185-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant TRAF1.
- Immunogen:
- TRAF1 (AAH24145, 1 a.a. ~ 416 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MASSSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGEDQICPKCRGEDLQSISPGSRLRTQEKAHPEVAEAGIGCPFAGVGCSFKGSPQSVQEHEVTSQTSHLNLLLGFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQEELALQHFMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLEQRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETST
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2b kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (71.5 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- In situ Proximity Ligation Assay (Cell)
- Proximity Ligation Analysis of protein-protein interactions between TRAF2 and TRAF1 HeLa cells were stained with anti-TRAF2 rabbit purified polyclonal 1:1200 and anti-TRAF1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- In situ Proximity Ligation Assay (Cell)
- enlarge
- Entrez GeneID:
- 7185
- GeneBank Accession#:
- BC024145
- Protein Accession#:
- AAH24145
- Gene Name:
- TRAF1
- Gene Alias:
- EBI6,MGC:10353
- Gene Description:
- TNF receptor-associated factor 1
- Omim ID:
- 601711
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. [provided by RefSeq
- Other Designations:
- Epstein-Bar virus-induced protein 6,OTTHUMP00000022000
- Gene Pathway
- Related Disease
- Alopecia Areata
- Alzheimer Disease
- Alzheimer disease
- Arthritis
- Arthritis, Juvenile Rheumatoid
- Arthritis, Rheumatoid
- Atherosclerosis
- Autoimmune Diseases
- Cardiovascular Diseases
- Celiac Disease
- Crohn's disease
- Diabetes Complications
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Progression
- Ductus Arteriosus, Patent
- Edema
- Endometriosis
- Genetic Predisposition to Disease