AIF1 polyclonal antibody
产品名称： AIF1 polyclonal antibody
英文名称： AIF1 polyclonal antibody
产品编号： PAB6990
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of AIF1.
- Immunogen:
- A synthetic peptide corresponding to human AIF1.
- Sequence:
- C-NKQFLDDPKYSSDED
- Host:
- Goat
- Theoretical MW (kDa):
- 16.7
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognize isoform 3 (NP_001614.3) only.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
Western blot (1-3 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Allograft inflammatory factor-1 (AIF-1) is crucial for the survival and pro-inflammatory activity of macrophages.
Yang ZF, Ho DW, Lau CK, Lam CT, Lum CT, Poon RT, Fan ST.Int Immunol. 2005 Nov;17(11):1391-7. Epub 2005 Sep 12.
- Applications
- Western Blot (Cell lysate)
- AIF1 polyclonal antibody (Cat # PAB6990) (1 ug/mL) staining of human PBMCs lysate (35 ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 199
- Protein Accession#:
- NP_001614.3
- Gene Name:
- AIF1
- Gene Alias:
- AIF-1,IBA1,IRT-1
- Gene Description:
- allograft inflammatory factor 1
- Omim ID:
- 601833
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000029354,OTTHUMP00000029356,interferon gamma responsive transcript,ionized calcium-binding adapter molecule