SPIRE1 monoclonal antibody (M01), clone 4C5
产品名称： SPIRE1 monoclonal antibody (M01), clone 4C5
英文名称： SPIRE1 monoclonal antibody (M01), clone 4C5
产品编号： H00056907-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant SPIRE1.
- Immunogen:
- SPIRE1 (NP_064533, 482 a.a. ~ 583 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- SEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.96 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Annexin A2-Dependent Polymerization of Actin Mediates Endosome Biogenesis.
Morel E, Parton RG, Gruenberg J.Dev Cell. 2009 Mar;16(3):445-57.
- 2.
- Actin S-Nitrosylation Inhibits Neutrophil {beta}2 Integrin Function.
Thom SR, Bhopale VM, Mancini DJ, Milovanova TN.J Biol Chem. 2008 Apr 18;283(16):10822-34. Epub 2008 Feb 18.
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of SPIRE1 expression in transfected 293T cell line by SPIRE1 monoclonal antibody (M01), clone 4C5.
Lane 1: SPIRE1 transfected lysate(15 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged SPIRE1 is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 56907
- GeneBank Accession#:
- NM_020148
- Protein Accession#:
- NP_064533
- Gene Name:
- SPIRE1
- Gene Alias:
- MGC150621,MGC150622,Spir-1
- Gene Description:
- spire homolog 1 (Drosophila)
- Omim ID:
- 609216
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]).[supplied by OMIM
- Other Designations:
- spire homolog 1
- Gene Pathway
- Related Disease