KREMEN1 (N-term) Peptide
产品名称： KREMEN1 (N-term) Peptide
英文名称： KREMEN1 (N-term) Peptide
产品编号： P2604
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of KREMEN1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human KREMEN1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Flow cytometry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling.
Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, Delius H, Hoppe D, Stannek P, Walter C, Glinka A, Niehrs C.Nature. 2002 Jun 6;417(6889):664-7. Epub 2002 May 26.
- 2.
- Molecular cloning and characterization of Kremen, a novel kringle-containing transmembrane protein.
Nakamura T, Aoki S, Kitajima K, Takahashi T, Matsumoto K, Nakamura T.Biochim Biophys Acta. 2001 Mar 19;1518(1-2):63-72.
- Entrez GeneID:
- 83999
- Protein Accession#:
- NP_001034659;Q96MU8
- Gene Name:
- KREMEN1
- Gene Alias:
- FLJ31863,KREMEM1,KREMEN,KRM1
- Gene Description:
- kringle containing transmembrane protein 1
- Omim ID:
- 609898
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000028977,kringle-coding gene marking the eye and the nose,kringle-containing transmembrane protein 1
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