DCN (Human) Recombinant Protein (P01)
产品名称： DCN (Human) Recombinant Protein (P01)
英文名称： DCN (Human) Recombinant Protein (P01)
产品编号： H00001634-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Human DCN full-length ORF ( AAH05322, 1 a.a. - 359 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK
- Theoretical MW (kDa):
- 65.23
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Publication Reference
- 1.
- Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm.
Ang LS, Boivin WA, Williams SJ, Zhao H, Abraham T, Carmine-Simmen K, McManus BM, Bleackley RC, Granville DJ.Cell Death Dis. 2011 Sep 8;2:e209. doi: 10.1038/cddis.2011.88.
- 2.
- Decorin Is a Novel VEGFR-2-Binding Antagonist for the Human Extravillous Trophoblast.
Khan GA, Girish GV, Lala N, Di Guglielmo GM, Lala PK.Mol Endocrinol. 2011 Jun 9. [Epub ahead of print]
- 3.
- Granzyme B Contributes to Extracellular Matrix Remodelling and Skin Aging in Apolipoprotein E Knockout Mice.
Hiebert PR, Boivin WA, Abraham T, Pazooki S, Zhao H, Granville DJ.Exp Gerontol. 2011 Feb 10. [Epub ahead of print]
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 1634
- GeneBank Accession#:
- BC005322
- Protein Accession#:
- AAH05322
- Gene Name:
- DCN
- Gene Alias:
- CSCD,DSPG2,PG40,PGII,PGS2,SLRR1B
- Gene Description:
- decorin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome. [provided by RefSeq
- Other Designations:
- bone proteoglycan II,decorin proteoglycan,dermatan sulphate proteoglycans II,proteoglycan core protein,small leucine-rich protein 1B
- Gene Pathway