RAD23A (N-term) Peptide
产品名称: RAD23A (N-term) Peptide
英文名称: RAD23A (N-term) Peptide
产品编号: P0993
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of RAD23A.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human RAD23A.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Structural determinants for the binding of ubiquitin-like domains to the proteasome.
Mueller TD, Feigon J.EMBO J. 2003 Sep 15;22(18):4634-45.
- 2.
- Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions.
Mueller TD, Feigon J.J Mol Biol. 2002 Jun 21;319(5):1243-55.
- 3.
- Involvement of rhp23, a Schizosaccharomyces pombe homolog of the human HHR23A and Saccharomyces cerevisiae RAD23 nucleotide excision repair genes, in cell cycle control and protein ubiquitination.
Elder RT, Song XQ, Chen M, Hopkins KM, Lieberman HB, Zhao Y.Nucleic Acids Res. 2002 Jan 15;30(2):581-91.
- Entrez GeneID:
- 5886
- Protein Accession#:
- R23A_HUMAN
- Gene Name:
- RAD23A
- Gene Alias:
- HHR23A,MGC111083
- Gene Description:
- RAD23 homolog A (S. cerevisiae)
- Omim ID:
- 600061
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. [provided by RefSeq
- Other Designations:
- RAD23, yeast homolog, A,UV excision repair protein RAD23 homolog A
- Gene Pathway