重组人CDNF-RNAi技术-试剂-生物在线
上海沪震实业有限公司
重组人CDNF

重组人CDNF

商家询价

产品名称： 重组人CDNF

英文名称： Recombinant Human Cerebral Dopamine Neurotrophic Factor

产品编号： HZ4672

产品价格： 0

产品产地： 中国/上海

品牌商标： 沪震生物

更新时间： 2023-08-17T10:24:20

使用范围： null

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 重组人CDNF

中文名称：重组人CDNF
英文名称：Recombinant Human Cerebral Dopamine Neurotrophic Factor
产品规格：5μg
分子量：Approximately 18.3kDa,a single non-glycosylated polypeptide chain containing 161 amino acids.
储存条件：冷冻（-20℃）

概述

Cerebral dopamine neurotrophic factor(CDNF),also known as ARMET-like protein 1,is encoded by the CDNF gene in humans and widely expressed in neuronal and non-neuronal tissues.The CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor(GDNF).Furthermore,it also prevents the 6-hydroxydopamine(6-OHDA)-induced degeneration of dopaminergic neurons.By research,CDNF might be beneficial for the treatment of Parkinsons disease.Recombinant human CDNF contains 162 amino acid residues and it shares 81%and 84%a.a.sequence identity with murine and rat CDNF.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观 Sterile Filtered White lyophilized(freeze-dried)powder.
纯度 ＞96%by SDS-PAGE and HPLC analyses.
来源 Escherichia coli.
生物活性 Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 25μg/ml,corresponding to a specific activity of>40 IU/mg.
成分 Lyophilized from a 0.2μmfiltered concentrated solution in 10mMPB,150 mM NaCl,pH 6.4,3%trehalose.
内毒素 Less than 1 EU/μg of rHuCDNF as determined by LAL method.
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列 QEAGGRPGAD CEVCKEFLNR FYKSLIDRGV NFSLDTIEKE LISFCLDTKG KENRLCYYLG ATKDAATKIL SEVTRPMSVH MPAMKICEKL KKLDSQICEL KYEKTLDLAS VDLRKMRVAE LKQILHSWGE ECRACAEKTD YVNLIQELAP KYAATHPKTE L

 

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