PLAT (Human) Recombinant Protein
产品名称: PLAT (Human) Recombinant Protein
英文名称: PLAT (Human) Recombinant Protein
产品编号: P3670
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human PLAT (P00750, 36 a.a. - 562 a.a.) partial recombinant protein expressed in CHO cells.
- Sequence:
- SYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP
- Theoretical MW (kDa):
- 60
- Form:
- Lyophilized
- Preparation Method:
- Mammalian cell (CHO) expression system
- Purification:
- Ion exchange column and HPLC reverse phase column
- Purity:
- > 98% by SDS-PAGE and HPLC
- Endotoxin Level:
- < 0.1 ng/ug (1 EU/ug)
- Activity:
- The activity was determined to be 6 x 105 IU/mg.
- Storage Buffer:
- Lyophilized from 0.2 M L-arginine, 0.1 M phosphoric acid
- Storage Instruction:
- Store at -20°C on dry atmosphere for 2 years.
After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.
Aliquot to avoid repeated freezing and thawing.
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 5327
- Protein Accession#:
- P00750
- Gene Name:
- PLAT
- Gene Alias:
- DKFZp686I03148,T-PA,TPA
- Gene Description:
- plasminogen activator, tissue
- Omim ID:
- 173370
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- alteplase,plasminogen activator, tissue type,reteplase,t-plasminogen activator,tissue plasminogen activator (t-PA)
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Aneurysm, Ruptured
- Arterial Occlusive Diseases
- Arteriosclerosis
- Arthritis, Rheumatoid
- Atherosclerosis
- Atherosclerosis
- Brain Infarction
- Brain Ischemia
- Calcinosis
- Cardiovascular Diseases
- Cerebral Palsy
- Cerebrovascular Accident
- Chorioamnionitis
- Connective Tissue Diseases
- Coronary Artery Disease
- Coronary Disease