Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Rat Interleukin-4 (Rat IL-4)
                
                

                
90169ES08
                
                

                
5 μg
                
                

                
815.00
                
            
            

                

                
90169ES60
                
                

                
100 μg
                
                

                
8515.00
                
            
            

                

                
90169ES76
                
                

                
500 μg
                
                

                
22115.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a pleiotropic cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells and produced by by mast cells, activated T cells and bone marrow stromal cells. Mature human IL-4 shares 55%, 39% and 43% aa sequence identity with bovine, mouse, and rat IL-4, respectively.It is a potent cytokine produced by T cells and to a lesser extent by tumor-associated natural killer cells, basophils, and mast cells. IL-4 is a differentiation factor for transforming growth factor-beta secreting Th3. And IL-4 activates two distinct signalling pathways through tyrosine phosphorylation of Stat6, a signal transducer and activator of transcription, and of a 170K protein called 4PS.
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
Interleukin-4, IL-4, BSF-1, BCDF, IL4E12, Pitrakinra
                
            
            

                

                
Accession
                
                

                
P20096
                
            
            

                

                
GeneID
                
                

                
287287
                
            
            

                

                
Source
                
                

                
E.coli-derived rat IL-4 protein, His23-Ser147.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 14.0 kDa.
                
            
            

                

                
AA Sequence
                
                

                
HGCNDSPLRE IINTLNQVTE KGTPCTEMFV PDVLTATRNT TENELICRAS RVLRKFYFPR DVPPCLKNKS GVLGELRKLC RGVSGLNSLR SCTVNESTLT TLKDFLESLK SILRGKYLQS CTSMS
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
Physical Appearance
                
                
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