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上海信裕生物科技有限公司
GAD2抗体

GAD2抗体

商家询价

产品名称： GAD2抗体

英文名称： GAD2Antibody

产品编号： XY21760-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 GAD2抗体

Applications
Tested Applications: ELISA, WB, IP
Specificity Reaction: Human, Mouse, Rat; Other species are not tested.Please decide the specificity by homology
Positive WB detected in Mouse brain tissue
Positive IP detected in Rat brain tissue
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:1000
 GAD2抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 21760-1-AP;mouse brain tissuemouse brain tissue were subjected to SDS PAGE followed by western blot with 21760-1-AP( GAD2 Antibody) at dilution of 1:600
  • 21760-1-AP;rat brain tissueIP Result of anti-GAD2 (IP:21760-1-AP, 3ug; Detection:21760-1-AP 1:300) with rat brain tissue lysate 4000ug.
Product Information GAD2抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: GAD2 fusion protein ag16251 Full Name: Glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Caculated Molecular
Weight:		 585aa,65 kDa Observed Molecular 
Weight:		 65 kDa
GenbankNo BC126327 GeneID: 2572
Symbol GAD2 Synonyms GAD 65, GAD2, GAD65, Glutamate decarboxylase 2
Background

GAD2, also named as GAD65, belongs to the group II decarboxylase family. GAD2 catalyzes the production of GABA. It is responsible for the synthesis of the essential neurotransmitter gamma-aminobutyric acid (GABA) from L-glutamic acid. GAD2is expressed in nervous and endocrine systems and are thought to be involved in synaptic transmission and insulin secretion. Autoantibodies against GAD2 may serve as markers for type I diabetes. Many individuals suffering from an adult onset disorder known as Stiff Person Syndrome (SPS) also express autoantibodies to GAD2. The antibody is specific to GAD2. GAD2抗体

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