APOE (Human) Recombinant Protein
产品名称： APOE (Human) Recombinant Protein
英文名称： APOE (Human) Recombinant Protein
产品编号： P4123
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human APOE (NP_000032.1, 299 amino acids) partial recombinant protein expressed in Escherichia coli.
- Sequence:
- MKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGTSAAPVPSDNH
- Theoretical MW (kDa):
- 34
- Form:
- Lyophilized
- Preparation Method:
- Escherichia coli expression system
- Purity:
- ≥ 90% by SDS-PAGE and HPLC
- Endotoxin Level:
- < 0.1 ng/ug
- Storage Buffer:
- Lyophilized from 20mM sodium phosphate
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with 5 mM sodium phosphate pH 7.8 containing 0.5 mM DTT, store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Application Image
- SDS-PAGE
- Entrez GeneID:
- 348
- GeneBank Accession#:
- NM_000041
- Protein Accession#:
- NP_000032.1
- Gene Name:
- APOE
- Gene Alias:
- AD2,LPG,MGC1571,apoprotein
- Gene Description:
- apolipoprotein E
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
- Other Designations:
- apolipoprotein E3
- Gene Pathway
- Related Disease
- Abortion, Habitual
- Achievement
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Adenoma
- AIDS Dementia Complex
- AIDS-Related Opportunistic Infections
- Akathisia, Drug-Induced
- Albuminuria
- Alcohol Amnestic Disorder
- Alcohol Withdrawal Seizures
- Alcoholism
- Alcohol-Related Disorders
- Alzheimer Disease
- Alzheimer disease
- Amnesia
- Amyloid Neuropathies, Familial
- Amyloidosis
- Amyotrophic Lateral Sclerosis