NMT2 (C-term) Peptide
产品名称： NMT2 (C-term) Peptide
英文名称： NMT2 (C-term) Peptide
产品编号： P1091
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NMT2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human NMT2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Operation profile of zebrafish guanylate cyclase-activating protein 3.
Fries R, Scholten A, Saftel W, Koch KW.J Neurochem. 2012 Apr;121(1):54-65. doi: 10.1111/j.1471-4159.2011.07643.x.
- 2.
- Myristoylation as a target for inhibiting HIV assembly: unsaturated fatty acids block viral budding.
Lindwasser OW, Resh MD.Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13037-42. Epub 2002 Sep 20.
- 3.
- Novel target genes of the Ah (dioxin) receptor: transcriptional induction of N-myristoyltransferase 2.
Kolluri SK, Balduf C, Hofmann M, Gottlicher M.Cancer Res. 2001 Dec 1;61(23):8534-9.
- 4.
- Myristoylation of human immunodeficiency virus type 1 gag protein is required for efficient env protein transportation to the surface of cells.
Shiraishi T, Misumi S, Takama M, Takahashi I, Shoji S.Biochem Biophys Res Commun. 2001 Apr 20;282(5):1201-5.
- Applications
- Western Blot (Tissue lysate)
- The NMT2 polyclonal antibody (Cat # PAB4314) is used in Western blot to detect NMT2 in mouse liver tissue lysate .
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with NMT2 polyclonal antibody (Cat # PAB4314) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . BC = breast carcinoma .
- Entrez GeneID:
- 9397
- Protein Accession#:
- NMT2_HUMAN
- Gene Name:
- NMT2
- Gene Alias:
- -
- Gene Description:
- N-myristoyltransferase 2
- Omim ID:
- 603801
- Gene Ontology:
- Hyperlink
- Gene Summary:
- N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019188,glycylpeptide N-tetradecanoyltransferase 2
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