GRK7 polyclonal antibody
产品名称： GRK7 polyclonal antibody
英文名称： GRK7 polyclonal antibody
产品编号： PAB4012
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GRK7.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GRK7.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Species-specific differences in expression of G-protein-coupled receptor kinase (GRK) 7 and GRK1 in mammalian cone photoreceptor cells: implications for cone cell phototransduction.
Weiss ER, Ducceschi MH, Horner TJ, Li A, Craft CM, Osawa S.J Neurosci. 2001 Dec 1;21(23):9175-84.
- 2.
- Characterization of human GRK7 as a potential cone opsin kinase.
Chen CK, Zhang K, Church-Kopish J, Huang W, Zhang H, Chen YJ, Frederick JM, Baehr W.Mol Vis. 2001 Dec 21;7:305-13.
- Applications
- Western Blot (Cell lysate)
- The GRK7 polyclonal antibody (Cat # PAB4012) is used in Western blot to detect GRK7 in A-375 cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with GRK7 polyclonal antibody (Cat # PAB4012) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 131890
- Protein Accession#:
- Q8WTQ7
- Gene Name:
- GRK7
- Gene Alias:
- GPRK7
- Gene Description:
- G protein-coupled receptor kinase 7
- Omim ID:
- 606987
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq
- Other Designations:
- G-protein-coupled receptor kinase 7
- Gene Pathway