Recombinant Rat SCF

Catalog Number:AF-400-22
Synonyms:

Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor
Description:

干细胞因子（SCF）是一种造血生长因子，通过经c-Kit受体的信号通路发挥其活性。SCF和c-Kit是造血干细胞、黑色素细胞和生殖细胞系生存，增殖和分化必不可少的。人SCF对小鼠细胞表现出低活性，但是小鼠和大鼠SCF对人类细胞具有充分的活性。重组大鼠SCF是分子量为18.4 kDa的多肽，含有165个氨基酸残基，其序列相当于分泌型可溶性形式的SCF的序列。生产过程中的所有试剂均为非动物源性。
AA Sequence:

MQEICRNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV THLSVSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVAC MEENAPKNVK ESLKKPETRN FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA
Source:E.coli
Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:

Determined by the dose-dependent stimulation of the proliferation of the human TF-1 cells. The expected ED50 for this effect is 20 - 40 ng/ml.
Cross Reactivity:Human