CNR1 (Human) Recombinant Protein (Q01)
产品名称: CNR1 (Human) Recombinant Protein (Q01)
英文名称: CNR1 (Human) Recombinant Protein (Q01)
产品编号: H00001268-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human CNR1 partial ORF ( NP_057167, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMV
- Theoretical MW (kDa):
- 37.84
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 1268
- GeneBank Accession#:
- NM_016083
- Protein Accession#:
- NP_057167
- Gene Name:
- CNR1
- Gene Alias:
- CANN6,CB-R,CB1,CB1A,CB1K5,CB1R,CNR
- Gene Description:
- cannabinoid receptor 1 (brain)
- Omim ID:
- 114610
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000016838,OTTHUMP00000016839,OTTHUMP00000016840,central cannabinoid receptor
- Gene Pathway
- Related Disease
- Acute Disease
- Affective Disorders, Psychotic
- Alcohol Withdrawal Delirium
- Alcohol Withdrawal Seizures
- Alcoholism
- Anorexia Nervosa
- Antisocial Personality Disorder
- Anxiety Disorders
- Arousal
- Asperger Syndrome
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Bipolar Disorder
- Bulimia
- Carcinoma
- Cardiovascular Diseases
- Cocaine-Related Disorders
- Cognition Disorders
- Colitis, Ulcerative