TTF1; NKX2-1抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
TTF1; NKX2-1抗体

TTF1; NKX2-1抗体

商家询价

产品名称： TTF1; NKX2-1抗体

英文名称： TTF1; NKX2-1Antibody

产品编号： XY21777-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 TTF1; NKX2-1抗体Applications

Tested Applications: ELISA, WB, IHC
Specificity Reaction: Human; Other species are not tested.Please decide the specificity by homology
Positive WB detected in HeLa cells, A549 cells
Positive IHC detected in Human lung cancer tissue
Recommended dilution WB : 1:500-1:5000
IHC : 1:20-1:200
 TTF1; NKX2-1抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 21777-1-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 21777-1-AP(NKX2-1 antibody) at dilution of 1:1000
  • 21777-1-AP;human lung cancer tissueImmunohistochemical of paraffin-embedded human lung cancer using 21777-1-AP(NKX2-1 antibody) at dilution of 1:50 (under 40x lens)
Product Information TTF1; NKX2-1抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: Peptide Full Name: NK2 homeobox 1
Caculated Molecular
Weight:		 42 kDa Observed Molecular 
Weight:		 41-45 kDa
GenbankNo NM_003317 GeneID: 7080
Symbol NKX2-1 Synonyms BHC, Homeobox protein Nkx 2.1, NK 2, NK2 homeobox 1, NKX2 1, NKX2.1, NKX2-1, NKX2A, TEBP, Thyroid nuclear factor 1, Thyroid transcription factor 1, TITF1, TTF 1, TTF1
Background

NKX2-1, also named as NKX2A, TITF1 and TTF1, belongs to the NK-2 homeobox family. It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. NKX2-1 is crucial in the maintenance of the thyroid differentiation phenotype. It may play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea (BHC), choreoathetosis, hypothyroidism, and neonatal respiratory distress (CHNRD). The antibody is specific to NKX2-1. TTF1; NKX2-1抗体

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