DPYD (Human) Recombinant Protein (Q01)
产品名称： DPYD (Human) Recombinant Protein (Q01)
英文名称： DPYD (Human) Recombinant Protein (Q01)
产品编号： H00001806-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human DPYD partial ORF ( NP_000101, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYY
- Theoretical MW (kDa):
- 37.84
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 1806
- GeneBank Accession#:
- NM_000110
- Protein Accession#:
- NP_000101
- Gene Name:
- DPYD
- Gene Alias:
- DHP,DHPDHASE,DPD,MGC132008,MGC70799
- Gene Description:
- dihydropyrimidine dehydrogenase
- Omim ID:
- 274270
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000037640,OTTHUMP00000058954,dihydrothymine dehydrogenase,dihydrouracil dehydrogenase
- Related Disease
- Adenocarcinoma
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Colon cancer
- Colonic Neoplasms
- Colorectal Neoplasms
- Diarrhea
- Dihydropyrimidine Dehydrogenase Deficiency
- Disease Progression
- Drug Toxicity
- Esophageal Neoplasms
- Gastrointestinal Diseases
- Genetic Predisposition to Disease
- Hearing Loss
- Hematologic Diseases
- Hematologic Neoplasms
- Kidney Diseases
- Kidney Failure, Chronic