KIT monoclonal antibody (M05), clone 5F6
产品名称： KIT monoclonal antibody (M05), clone 5F6
英文名称： KIT monoclonal antibody (M05), clone 5F6
产品编号： H00003815-M05
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： 2023-09-20T22:25:31
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant KIT.
- Immunogen:
- KIT (NP_000213, 41 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- PGKSDLIVRVGDEIRLLCTDPGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLVDRSLYGKEDNDTLVRCPLTD
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2b Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of KIT expression in transfected 293T cell line by KIT monoclonal antibody (M05), clone 5F6.
Lane 1: KIT transfected lysate(109.865 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to KIT on formalin-fixed paraffin-embedded human stomach carcinoma. [antibody concentration 1.5 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged KIT is 0.03 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 3815
- GeneBank Accession#:
- NM_000222
- Protein Accession#:
- NP_000213
- Gene Name:
- KIT
- Gene Alias:
- C-Kit,CD117,PBT,SCFR
- Gene Description:
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- mast/stem cell growth factor receptor,proto-oncogene tyrosine-protein kinase Kit,soluble KIT variant 1
- Interactome
- Related Disease
- Acute Disease
- Aneuploidy
- Azoospermia
- Chronic Disease
- Constipation
- Disease Progression
- Gastrointestinal Stromal Tumors
- Genetic Predisposition to Disease
- Hematologic Neoplasms
- Hyperpigmentation
- Infertility, Male
- Leukemia, Myelocytic, Acute
- Leukemia, Myeloid
- Leukemia, Myeloid, Acute
- Leukemia, Promyelocytic, Acute
- Liver Neoplasms
- Lung Neoplasms
- Malignant melanoma
- Mastocytosis, Cutaneous