HLA-A2 monoclonal antibody, clone BB7.2
产品名称: HLA-A2 monoclonal antibody, clone BB7.2
英文名称: HLA-A2 monoclonal antibody, clone BB7.2
产品编号: MAB6434
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against HLA-A2.
- Immunogen:
- HLA-A2 solubilised by papain.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody recognizes an epitope at the C-terminus of alpha-2 helix and a turn onone of the underlying beta strands within the human HLA-A2 histocompatibility antigen.
- Form:
- Liquid
- Concentration:
- 1 mg/mL
- Isotype:
- IgG2b
- Storage Buffer:
- In PBS, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A simplified PCR-SSP method for HLA-A2 subtype in a population of Wuhan, China.
Liang B, Zhu L, Liang Z, Weng X, Lu X, Zhang C, Li H, Wu X.Cell Mol Immunol. 2006 Dec;3(6):453-8.
- 2.
- Induction of ovarian tumor-specific CD8+ cytotoxic T lymphocytes by acid-eluted peptide-pulsed autologous dendritic cells.
Santin AD, Bellone S, Ravaggi A, Pecorelli S, Cannon MJ, Parham GP.Obstet Gynecol. 2000 Sep;96(3):422-30.
- 3.
- Isolation of broadly reactive, tumor-specific, HLA Class-I restricted CTL from blood lymphocytes of a breast cancer patient.
Verdegaal EM, Huinink DB, Hoogstraten C, Marijnissen AK, Gorsira MB, Claas FH, Osanto S.Hum Immunol. 1999 Dec;60(12):1195-206.
- Application Image
- Immunoprecipitation
- Flow Cytometry
- Entrez GeneID:
- 3105
- Gene Name:
- HLA-A
- Gene Alias:
- HLAA
- Gene Description:
- major histocompatibility complex, class I, A
- Gene Ontology:
- Hyperlink
- Gene Summary:
- HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq
- Other Designations:
- HLA class I histocompatibility antigen, A-23 alpha chain,MHC class I antigen HLA-A heavy chain,MHC leukocyte antigen,OTTHUMP00000161059,antigen presenting molecule,leucocyte antigen class I,leukocyte antigen class I-A
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- Abortion, Habitual
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