EPHA1 polyclonal antibody
产品名称： EPHA1 polyclonal antibody
英文名称： EPHA1 polyclonal antibody
产品编号： PAB3002
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of EPHA1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human EPHA1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The DNA sequence of human chromosome 7.
Hillier LW, Fulton RS, Fulton LA, Graves TA, Pepin KH, Wagner-McPherson C, Layman D, Maas J, Jaeger S, Walker R, Wylie K, Sekhon M, Becker MC, O'Laughlin MD, Schaller ME, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Cordes M, Du H, Sun H, Edwards J, Bradshaw-Cordum H, Ali J, Andrews S, Isak A, Vanbrunt A, Nguyen C, Du F, Lamar B, Courtney L, Kalicki J, Ozersky P, Bielicki L, Scott K, Holmes A, Harkins R, Harris A, Strong CM, Hou S, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Leonard S,Nature. 2003 Jul 10;424(6945):157-64.
- 2.
- Genomic structure of the EPHA1 receptor tyrosine kinase gene.
Owshalimpur D, Kelley MJ.Mol Cell Probes. 1999 Jun;13(3):169-73.
- 3.
- A novel putative tyrosine kinase receptor encoded by the eph gene.
Hirai H, Maru Y, Hagiwara K, Nishida J, Takaku F.Science. 1987 Dec 18;238(4834):1717-20.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of EPHA1 polyclonal antibody (Cat # PAB3002) in HeLa cell lysate. EPHA1 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 2041
- Protein Accession#:
- P21709
- Gene Name:
- EPHA1
- Gene Alias:
- EPH,EPHT,EPHT1,MGC163163
- Gene Description:
- EPH receptor A1
- Omim ID:
- 179610
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq
- Other Designations:
- eph tyrosine kinase 1,ephrin receptor EphA1,ephrin type-A receptor 1,erythropoietin-producing hepatoma amplified sequence,oncogene EPH,soluble EPHA1 variant 1,soluble EPHA1 variant 2,tyrosine-protein kinase receptor EPH
- Gene Pathway
- Related Disease