Cd86 monoclonal antibody, clone GL1 (PE)
产品名称： Cd86 monoclonal antibody, clone GL1 (PE)
英文名称： Cd86 monoclonal antibody, clone GL1 (PE)
产品编号： MAB5753
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rat monoclonal antibody raised against native Cd86.
- Immunogen:
- Native purified Cd86 from LPS-activated mouse B cells.
- Host:
- Rat
- Reactivity:
- Mouse
- Specificity:
- Mouse CD86, the B7-2 co-stimulatory molecule and a ligand for CD28 and CD152/CTLA-4.
- Form:
- Liquid
- Conjugation:
- PE
- Isotype:
- IgG2a, kappa
- Storage Buffer:
- In PBS (0.1 mg/mL sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (0.1 ug/106 cells)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro.
Inaba K, Witmer-Pack M, Inaba M, Hathcock KS, Sakuta H, Azuma M, Yagita H, Okumura K, Linsley PS, Ikehara S, Muramatsu S, Hodes RJ, Steinman RM.J Exp Med. 1994 Nov 1;180(5):1849-60.
- 2.
- Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function.
Hathcock KS, Laszlo G, Pucillo C, Linsley P, Hodes RJ.J Exp Med. 1994 Aug 1;180(2):631-40.
- 3.
- Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice.
Freeman GJ, Borriello F, Hodes RJ, Reiser H, Hathcock KS, Laszlo G, McKnight AJ, Kim J, Du L, Lombard DB, et al..Science. 1993 Nov 5;262(5135):907-9.
- Applications
- Flow Cytometry
- BALB/c spleen cells were activated by incubation for 72 hours with LPS. The cells were then harvested and stained with Cd86 monoclonal antibody, clone GL1 (FITC) (Cat # MAB5751). A wide gate was set to include small, medium and large cells, following which the cells were analyzed on a FACScan™ flow cytometer (BDIS, San Jose, CA).
- Entrez GeneID:
- 12524
- Gene Name:
- Cd86
- Gene Alias:
- B7,B7-2,B7.2,B70,CLS1,Cd28l2,ETC-1,Ly-58,Ly58,MB7,MB7-2,TS/A-2
- Gene Description:
- CD86 antigen
- Gene Ontology:
- Hyperlink
- Other Designations:
- OTTMUSP00000015940,T-lymphocyte activation antigen CD86,activation B7-2 antigen,early T cell costimulatory molecule-1
- Interactome
