KRAS (Human) Recombinant Protein (Q01)
产品名称: KRAS (Human) Recombinant Protein (Q01)
英文名称: KRAS (Human) Recombinant Protein (Q01)
产品编号: H00003845-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human KRAS partial ORF ( NP_004976, 16 a.a. - 125 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTV
- Theoretical MW (kDa):
- 37.84
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 3845
- GeneBank Accession#:
- NM_004985
- Protein Accession#:
- NP_004976
- Gene Name:
- KRAS
- Gene Alias:
- C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS3,RASK2
- Gene Description:
- v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq
- Other Designations:
- K-ras p21 protein,Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog,PR310 c-K-ras oncogene,c-K-ras2 protein,c-Kirsten-ras protein,cellular c-Ki-ras2 proto-oncogene,oncogene KRAS2,transforming protein p21,v-Ki-ras2 Kirsten rat sarcoma 2 viral oncoge
- Gene Pathway
- Acute myeloid leukemia
- Axon guidance
- B cell receptor signaling pathway
- Bladder cancer
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Colorectal cancer
- Dorso-ventral axis formation
- Endometrial cancer
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Gap junction
- Glioma
- GnRH signaling pathway
- Insulin signaling pathway
- Long-term depression
- Long-term potentiation
- MAPK signaling pathway
- Melanogenesis
- Melanoma
- Natural killer cell mediated cytotoxicity
- Neurotrophin signaling pathway
- Non-small cell lung cancer
- Pancreatic cancer
- Pathways in cancer
- Prostate cancer
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- T cell receptor signaling pathway
- Thyroid cancer
- Tight junction
- VEGF signaling pathway
- Related Disease
- Abnormalities, Multiple
- Acute Disease
- Adenocarcinoma
- Adenocarcinoma, Bronchiolo-Alveolar
- Adenocarcinoma, Mucinous
- Adenocarcinoma, Papillary
- Adenoma
- Adenomatous Polyposis Coli
- Alcoholism
- Anus Neoplasms
- Biliary Tract Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Adenosquamous
- Carcinoma, Endometrioid
- Carcinoma, Giant Cell
- Carcinoma, Large Cell
- Carcinoma, Medullary