AKR1C3 MaxPab mouse polyclonal antibody (B02)
产品名称： AKR1C3 MaxPab mouse polyclonal antibody (B02)
英文名称： AKR1C3 MaxPab mouse polyclonal antibody (B02)
产品编号： H00008644-B02
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human AKR1C3 protein.
- Immunogen:
- AKR1C3 (NP_003730.4, 1 a.a. ~ 323 a.a) full-length human protein.
- Sequence:
- MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYSDEY
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- AKR1C3 MaxPab polyclonal antibody. Western Blot analysis of AKR1C3 expression in human liver.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of AKR1C3 expression in transfected 293T cell line (H00008644-T02) by AKR1C3 MaxPab polyclonal antibody.
Lane 1: AKR1C3 transfected lysate(35.53 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 8644
- GeneBank Accession#:
- NM_003739.4
- Protein Accession#:
- NP_003730.4
- Gene Name:
- AKR1C3
- Gene Alias:
- DD3,DDX,HA1753,HAKRB,HAKRe,HSD17B5,KIAA0119,hluPGFS
- Gene Description:
- aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
- Omim ID:
- 603966
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq
- Other Designations:
- OTTHUMP00000018996,aldo-keto reductase family 1, member C3,chlordecone reductase,dihydrodiol dehydrogenase 3,dihydrodiol dehydrogenase X,hydroxysteroid (17-beta) dehydrogenase 5,prostaglandin F synthase,trans-1,2-dihydrobenzene-1,2-diol dehydrogenase,type
- Related Disease
- Adenocarcinoma
- Breast cancer
- Breast Neoplasms
- Ductus Arteriosus, Patent
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Hyperandrogenism
- Infant, Premature, Diseases
- Leukemia
- Leukemia, chronic myeloid
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Leukemia, Myeloid, Acute
- Lung Neoplasms
- Lymphoma, Non-Hodgkin
- Neoplasms, Hormone-Dependent
- Obesity
- Ovarian cancer
- Ovarian Failure, Premature
- Ovarian Neoplasms