Human Growth Factors & Cytokines
Recombinant Human gAcrp30/Adipolean





 





		Synonyms :
apm-1, Adipolean (human)



		Description :
gAcrp30 is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin.  Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein.  Like Adiponectin, gAcrp30 is capable of decreasing hyperglycemia and reversing insulin resistance.  Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids (FFAs).  The signaling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2.  AdipoR2 is predominantly expressed in the liver.  Recombinant human gAcrp30/Adipolean is a 16.6 kDa protein consisting of 145 amino acid residues.



		Catalog #:
450-21



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.2 ng per μg (2EU/μg).



		Biological Activity :
Determined by its ability to inhibit the proliferation of murine M1 cells.  The expected ED50 for this effect is 1.0-3.0 μg/ml.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
MKGEPGEGAY VYRSAFSVGL ETYVTIPNMP IRFTKIFYNQ QNHYDGSTGK FHCNIPGLYY FAYHITVYMK DVKVSLFKKD KAMLFTYDQY QENNVDQASG SVLLHLEVGD QVWLQVYGEG ERNGLYADND NDSTFTGFLL YHDTN 



		PubMed Link :
apm-1+AND+adipocyte


Country of Origin :
USA
















        Size A
5μg
$80 
 


 



        Size B
25μg
$195 
 


 



        Size C
1mg
$3000 
 


 















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.