MAGI1 polyclonal antibody
产品名称： MAGI1 polyclonal antibody
英文名称： MAGI1 polyclonal antibody
产品编号： PAB2150
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAGI1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MAGI1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1.
Patrie KM, Drescher AJ, Welihinda A, Mundel P, Margolis B.J Biol Chem. 2002 Aug 16;277(33):30183-90. Epub 2002 May 31.
- 2.
- Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.
Wood JD, Yuan J, Margolis RL, Colomer V, Duan K, Kushi J, Kaminsky Z, Kleiderlein JJ, Sharp AH, Ross CA.Mol Cell Neurosci. 1998 Jun;11(3):149-60.
- 3.
- Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1.
Shiratsuchi T, Futamura M, Oda K, Nishimori H, Nakamura Y, Tokino T.Biochem Biophys Res Commun. 1998 Jun 29;247(3):597-604.
- Applications
- Western Blot (Tissue lysate)
- The MAGI1 polyclonal antibody (Cat # PAB2150) is used in Western blot to detect MAGI1 in mouse brain tissue lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with MAGI1 polyclonal antibody (Cat # PAB2150) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Entrez GeneID:
- 9223
- Protein Accession#:
- NP_004733
- Gene Name:
- MAGI1
- Gene Alias:
- AIP3,BAIAP1,BAP1,MAGI-1,TNRC19,WWP3
- Gene Description:
- membrane associated guanylate kinase, WW and PDZ domain containing 1
- Omim ID:
- 602625
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- BAI1-associated protein 1,WW domain-containing protein 3,atrophin-1 interacting protein 3,membrane associated guanylate kinase inverted-1,trinucleotide repeat-containing gene 19
- Gene Pathway
- Related Disease