PSMB8 monoclonal antibody, clone 1A5
产品名称： PSMB8 monoclonal antibody, clone 1A5
英文名称： PSMB8 monoclonal antibody, clone 1A5
产品编号： MAB10306
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant PSMB8.
- Immunogen:
- Recombinant protein corresponding to human PSMB8.
- Host:
- Mouse
- Theoretical MW (kDa):
- 30
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis using PSMB8 monoclonal antobody, clone 1A5 (Cat # MAB10306) against HeLa (1), MCF-7 (2), A-431 (3), RAJI (4), MOTL4 (5) and PC-12 (6) cell lysate.
- Western Blot (Recombinant protein)
- Western blot analysis using PSMB8 monoclonal antobody, clone 1A5 (Cat # MAB10306) against recombinant human PSMB8 protein.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human intima cancer tissue (A) and colon tissue (B) using PSMB8 monoclonal antobody, clone 1A5 (Cat # MAB10306) with DAB staining.
- Entrez GeneID:
- 5696
- Gene Name:
- PSMB8
- Gene Alias:
- D6S216,D6S216E,LMP7,MGC1491,PSMB5i,RING10,beta5i
- Gene Description:
- proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
- Omim ID:
- 177046
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. [provided by RefSeq
- Other Designations:
- OTTHUMP00000029420,OTTHUMP00000029421,OTTHUMP00000062981,low molecular weight protein 7,macropain subunit C13,multicatalytic endopeptidase complex subunit C13,protease component C13,proteasome (prosome, macropain) subunit beta type 8 (large multifunctiona
- Gene Pathway
- Related Disease
- Acute Disease
- Alveolitis, Extrinsic Allergic
- Arthritis, Juvenile Rheumatoid
- Arthritis, Reactive
- Asthma
- Asthma
- Bronchiolitis, Viral
- Brucellosis
- Cardiovascular Diseases
- Coronary Disease
- Dermatitis, Atopic
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diseases in Twins
- Edema
- Genetic Predisposition to Disease
- Hepatitis B
- Hepatitis C
- Hepatitis C, Chronic