CYP2J2 monoclonal antibody (M01), clone 2D10
产品名称： CYP2J2 monoclonal antibody (M01), clone 2D10
英文名称： CYP2J2 monoclonal antibody (M01), clone 2D10
产品编号： H00001573-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant CYP2J2.
- Immunogen:
- CYP2J2 (NP_000766, 408 a.a. ~ 498 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- LHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRMGITISPVSHRLCA
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.75 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- CYP2J2 Expression and Circulating Epoxyeicosatrienoic Metabolites in Preeclampsia.
Herse F, Lamarca B, Hubel CA, Kaartokallio T, Lokki AI, Ekholm E, Laivuori H, Gauster M, Huppertz B, Sugulle M, Ryan MJ, Novotny S, Brewer J, Park JK, Kacik M, Hoyer J, Verlohren S, Wallukat G, Rothe M, Luft FC, Muller DN, Schunck WH, Staff AC, Dechend R.Circulation. 2012 Dec 18;126(25):2990-9. doi: 10.1161/CIRCULATIONAHA.112.127340. Epub 2012 Nov 15.
- 2.
- Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity.
Lee CA, Jones JP 3rd, Katayama J, Kaspera R, Jiang Y, Freiwald S, Smith E, Walker GS, Totah RA.Drug Metab Dispos. 2012 May;40(5):943-51. Epub 2012 Feb 10.
- 3.
- Detection of EETs and HETEs-generating Cytochrome P450 Enzymes and the Effects of their Metabolites on Myometrial and Vascular Function.
Pearson T, Warren AY, Barrett DA, Khan RN.Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E647-56. Epub 2009 Jun 23.
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged CYP2J2 is approximately 3ng/ml as a capture antibody.
- Protocol Download
- Application Image
- Western Blot (Recombinant protein)
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- Entrez GeneID:
- 1573
- GeneBank Accession#:
- NM_000775
- Protein Accession#:
- NP_000766
- Gene Name:
- CYP2J2
- Gene Alias:
- CPJ2
- Gene Description:
- cytochrome P450, family 2, subfamily J, polypeptide 2
- Omim ID:
- 601258
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. [provided by RefSeq
- Other Designations:
- OTTHUMP00000010550,arachidonic acid epoxygenase,cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2,flavoprotein-linked monooxygenase,microsomal monooxygenase
- Related Disease
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Body Weight
- Cardiovascular Diseases
- Coronary Artery Disease
- Coronary Disease
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- Glomerulonephritis, IGA
- Hypertension
- Insulin Resistance
- Kidney Failure, Chronic
- Myocardial Infarction
- Myocardial Ischemia