Human Growth Factors & Cytokines
Recombinant Human FGF-basic


 
 
Synonyms :
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
Description :
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.
Catalog #:
100-18B
Source :
E.coli
Purity :
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Biological Activity :
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. 

Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Selected References :
Selected List of References Citing This PeproTech Product
AA Sequence :
AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS 
PubMed Link :
FGF-2
Country of Origin :
USA
 
 
Size A
10μg
$80 
 
 
Size B
50μg
$195 
 
 
Size C
1mg
$1200 
 
 
 
 
Special Sizes: 
Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.
 
Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.