PKM2 monoclonal antibody
产品名称： PKM2 monoclonal antibody
英文名称： PKM2 monoclonal antibody
产品编号： MAB8733
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant PKM2.
- Immunogen:
- Recombinant protein corresponding to N-terminus residues of human PKM2.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody is specific to PKM2.
- Form:
- Liquid
- Purification:
- Protein G purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, pH 7.4 (0.02% sodium azide, 1% BSA, 50% glycerol)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:100-1:2000)
ELISA (1:5000-1:20000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 5315
- GeneBank Accession#:
- NM_182471.1
- Gene Name:
- PKM2
- Gene Alias:
- CTHBP,MGC3932,OIP3,PK3,PKM,TCB,THBP1
- Gene Description:
- pyruvate kinase, muscle
- Omim ID:
- 179050
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- OPA-interacting protein 3,PK, muscle type,pyruvate kinase M2,thyroid hormone-binding protein, cytosolic
- Interactome
- Gene Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Carbon fixation in photosynthetic organisms
- Glycolysis / Gluconeogenesis
- Metabolic pathways
- Purine metabolism
- Pyruvate metabolism
- Type II diabetes mellitus
- Related Disease