人的Nischarin Elisa试剂盒
产品名称: 人的Nischarin Elisa试剂盒
英文名称: Human Nischarin (NISCH) ELISA Kit
产品编号: E90249Hu
产品价格: 0
产品产地: 中国
品牌商标: USCN
更新时间: 2023-09-19T20:35:30
使用范围: null
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中文名称:人的Nischarin (NISCH)酶联免疫吸附测定试剂盒
英文名称:Human Nischarin (NISCH) ELISA Kit
产品规格:96T/48T
属于科研产品,不得用于临床
Nischarin acts either as the functional imidazoline-1 receptor (I1R) candidate or as a membrane-associated
mediator of the I1R signaling. Binds numerous imidazoline ligands that induces initiation of
cell-signaling cascades triggering to cell survival, growth and migration. Its activation by the agonist
rilmenidine induces an increase in phosphorylation of mitogen-activated protein kinases MAPK1 and MAPK3
in rostral ventrolateral medulla (RVLM) neurons that exhibited rilmenidine-evoked hypotension. Blocking
its activation with efaroxan abolished rilmenidine-induced mitogen-activated protein kinase phosphorylation
in RVLM neurons. Acts as a modulator of Rac-regulated signal transduction pathways. Suppresses Rac1-stimulated
cell migration by interacting with PAK1 and inhibiting its kinase activity.
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