Recombinant mouse CD160 protein, C-His Tag (HEK293)
重组小鼠CD160蛋白
英文名称 | Recombinant mouse CD160 protein, C-His Tag (HEK293) |
中文名称 | 重组小鼠CD160蛋白 |
别 名 | By55; Natural killer cell receptor BY55; BY55; CD160 antigen [Precursor]; CD160 molecule; FLJ46513; Natural killer cell receptor BY55; NK1; NK28; BY55_HUMAN; Recombinant mouse CD160 protein, C-His Tag (HEK293) |
理论分子量 | 19.9kDa |
性 状 | Lyophilized or Liquid |
浓 度 | >0.5 mg/ml |
物 种 | Mouse |
序 列 | 28-160/185 |
纯 度 | >90% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | Not analyzed |
表达系统 | HEK293 cell |
活性 | Not tested |
标签 | C-His Tag |
缓 冲 液 | PBS (pH=7.4) |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008] |
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本产品仅供科研使用.请勿用于医药,不能用于临床治疗诊断使用!