Recombinant human IL-6R-Beta protein, C-hFc-His (HEK293)
重组人白细胞介素6受体β蛋白
英文名称 | Recombinant human IL-6R-Beta protein, C-hFc-His (HEK293) |
中文名称 | 重组人白细胞介素6受体β蛋白 |
别 名 | IL-6R Beta; Interleukin-6 receptor subunit beta; Interleukin-6 signal transducer; Membrane glycoprotein 130; gp130; CDw130; Oncostatin-M receptor subunit alpha; CD_antigen; CD130; GP130 RAPS; gp130 transducer chain; GP130-RAPS; IL6 ST; IL6R-beta; IL6ST.IL6R-beta; Recombinant human IL-6R-Beta protein, C-hFc-His (HEK293) |
理论分子量 | 95.2kDa |
性 状 | Lyophilized or Liquid |
浓 度 | >0.5 mg/ml |
物 种 | Human |
序 列 | 23-618/618 |
纯 度 | >90% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | Not analyzed |
表达系统 | HEK293 cell |
活性 | Not tested |
标签 | C-hFc-His |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014 |
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本产品仅供科研使用.请勿用于医药,不能用于临床治疗诊断使用!